From: Neutrophils to lymphocytes ratio as a useful prognosticator for stage II colorectal cancer patients
Parameter | NLR (Median + IR) | p value |
---|---|---|
Gender | ||
 Male | 2.59 (2.05–3.32) | NS |
 Female | 2.51 (1.87–3.69) | |
Age | ||
  ≥ 72 years | 2.72 (2.14–3.76) | 0.016 |
  < 72 years | 2.41 (1.82–3.16) | |
Primary tumor | ||
 Right colon | 2.67 (2.13–3.76) |  |
 Left colon | 2.65 (1.89–3.42) | |
 Rectum | 2.48 (1.81–3.08) | |
 Right VS Left colon | 2.67 (2.13–3.76) VS 2.49 (1.85–3.24) | NS |
 Colon VS Rectum | 2.67 (2.10–3.68) VS 2.48 (1.81–3.08) | NS |
Differentiation | ||
 Low | 2.7 (2.2–3.44) | NS |
 Medium + High | 2.51 (1.88–3.4) | |
T | ||
 T1 | 1.88 (1.53–2.98) | NS |
 T2 | 2.49 (1.85–3.14) | |
 T3 | 2.6 (2.0–3.43) | |
 T4 | 2.76 (2.27–5.22) | |
N | ||
 N0 | 2.58 (1.92–3.37) | NS |
 N1 | 2.34 (1.85–3.45) | |
 N2 | 2.78 (2.29–3.95) | |
No of lymph node harvested | ||
  < 12 | 2.37 (2.09–3.28) | NS |
  ≥ 12 | 2.58 (1.92–3.43) | |
No of infiltrated lymph nodes | ||
 0 (n = 198) | 2.58 (1.96–3.43) | NS |
 1 (n = 21) | 2.22 (1.73–3.82) | |
  ≥ 2 (n = 77) | 2.55 (1.91–3.33) | |
Stage | ||
 Stage I | 2.26 (1.74–2.87) | 0.049 |
 Stage II | 2.67 (2.16–3.45) | |
 Stage III | 2.55 (1.96–3.60) | |
 Stage I VS Stage II + III | 2.26 (1.74–2.87) VS 2.62 (2.07–3.48) | |
Perineural invasion | ||
 No | 2.53 (1.91–3.30) | < 0.001 |
 Yes | 3.45 (2.24–6.00) | |
Vascular invasion | ||
 No | 2.54 (1.91–3.36) | 0.034 |
 Yes | 2.68 (2.17–4.18) | |
Lymphatic invasion | ||
 No | 2.53 (1.91–3.40) | NS |
 Yes | 2.63 (2.12–3.69) | |
Recurrence | ||
 No | 2.54 (1.96–3.37) | NS |
 Yes | 2.79 (1.83–4.03) | |
Site of recurrence | ||
 Local (n = 15) | 2.11 (1.56–4.03) | NS |
 Distant (n = 16) | 3.05 (2.07–3.89) |