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Fig. 5 | BMC Cancer

Fig. 5

From: Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells

Fig. 5

Effects of ATRA on motility of MCF10DCIS cells. a Representative phase-contrast images of MCF10DCIS cells grown on plastic dishes under hypoxia for 96 h in the presence of 1 μM ATRA or DMSO (vehicle). The number of cells with an elongated shape is shown on the right. Bar: 20 μm. b Dynamic monitoring of migration of MCF10DCIS cultured under normoxic or hypoxic conditions for 96 h in the presence or absence of 1 μM ATRA. Fold changes in the slope compared with normoxia are reported. Error bars indicate ± SD from a quadruplicate experiment. *P < 0.05 between bars; #P < 0.05 with respect to normoxia taken as 1

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BMC Cancer

ISSN: 1471-2407

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