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Fig. 3 | BMC Cancer

Fig. 3

From: Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells

Fig. 3

Responsiveness of MCF10DCIS cells to ATRA under normoxia. a Representative Western blot analysis with the indicated antibodies of lysates from MCF10DCIS cells grown in the presence of ATRA with indicated concentrations for the indicated times under normoxia. Immunoblots shown have been cropped to conserve space. b Levels of RARα as deduced from the densitometry of immunochemical bands normalized with β-Tubulin, used as internal control for equivalence of loaded proteins. c Proliferation of MCF10DCIS cells cultured in the presence of different concentrations of ATRA for the indicated times. All the data are the mean of three separate experiments performed in triplicate ±SD. #P < 0.05 with respect to the untreated condition taken as 1

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