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Table 1 Characteristics of 50 NPC patients

From: Circulating tumor cells with karyotyping as a novel biomarker for diagnosis and treatment of nasopharyngeal carcinoma

Characteristics Total No. of patients
Newly diagnosis (M0, N = 29) Relapse/Distant metastasis after treatment (N = 21)
Gender
 Male 34 19 15
 Female 16 10 6
Age (years)
Median (Range) 48 (17–66) 47 (17–66) 49(20–66)
  < 50 29 17 12
  ≥ 50 21 12 9
Pathology type
 WHO I 1 1 0
 WHO II/III 49 28 21
Stagea
T-classification
 T1 7 5 2
 T2 8 5 3
 T3 13 7 6
 T4 22 12 10
N-classification
 N0 4 3 1
 N1 8 1 7
 N2 29 20 9
 N3 9 5 4
TNM stage
 I 0 0 0
 II 4 2 2
 III 19 12 7
 IV 27 15 12
Treatmentb
IndCT+RT/CCRT 29 29 0
 CT ± RT 15 0 15
 Others 6 0 6
pEBV DNA level
 Negative 7 2 5
 Positive 43 27 16
  1. a Stage for patients with relapse/distant metastasis after treatment refered to TNM stage at NPC initial diagnosis
  2. b IndCT = induction chemotherapy, CT = Chemotherapy, RT = radiotherapy, CCRT = concurrent chemoradiotherapy