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Fig. 4 | BMC Cancer

Fig. 4

From: Effects of PKM2 on global metabolic changes and prognosis in hepatocellular carcinoma: from gene expression to drug discovery

Fig. 4

Personalized expression and survival analysis of PKM2-correlated deregulated genes. The heatmap shows the personalized log2 fold changes of these genes in the high-PKM2 (≥ 11.25) and low-PKM2 (< 11.25) groups. The personalized fold changes were calculated as the gene expression values for each patient/mean expression of the gene in controls. For survival analysis, the reference group of up-regulated genes was defined as patients with levels below the median expression level of the gene, and the reference group of down-regulated genes was defined as patients with levels higher than the median expression level of the gene

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