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Fig. 6 | BMC Cancer

Fig. 6

From: miR-663a inhibits tumor growth and invasion by regulating TGF-β1 in hepatocellular carcinoma

Fig. 6

miR-663a suppressed tumorigenesis in vivo. a Tumor formation in nude mice 4 weeks after injection with Huh-7- pLenti-miR-663a and Huh-7- pLenti-NC. b Growth curve of Huh-7- pLenti-miR-663a and Huh-7- pLenti-NC-formed tumors. Volumes of the tumors were measured every 3 days. (Data are presented as mean ± SD (n = 6)). c Volumes of the Huh-7- pLenti-miR-663a and Huh-7- pLenti-NC-formed tumors 4 weeks after the initial injection. d Weights of the Huh-7- pLenti-miR-663a and Huh-7- pLenti-NC-formed tumors 4 weeks after the initial injection. e The expression of miR-663a and TGF-β1 was detected by qRT–PCR in the mouse tumor tissues induced by Huh-7- pLenti-miR-663a and Huh-7- pLenti-NC. (Data are presented as mean ± SD (n = 3)). f The expression of TGF-β1 in tumor tissues was measured by immunohistochemistry and HE staining. Representative fields are shown (400×). **p < 0.01, ***p < 0.001

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