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Table 1 Baseline demographic and tumor characteristics of patients in SEER database

From: Does fibrosis have an impact on survival of patients with hepatocellular carcinoma: evidence from the SEER database?

Variables Fibrosis Score P Value
0–4 5–6
Age, years 62.8 ± 11.8 61.0 ± 9.2 < 0.001
Age <  60 931(40.1) 4457(47.1) < 0.001
≥ 60 1390(59.9) 5005(52.9)  
Sex Male 1804(77.7) 7471(79.0) 0.194
Female 517(22.3) 1991(21.0)  
Ethnicity White 1352(58.2) 6709(70.9) < 0.001
Asian or Pacific Island 621(26.7) 1448(15.3)  
Black 312(13.5) 1101(11.6)  
American Indian/Alaska Native 25(1.1) 157(1.7)  
Unknown 11(0.5) 47(0.5)  
Marital Status Married 1298(55.9) 4818(50.9) < 0.001
Unmarried 932(40.2) 4303(45.5)  
Unknown 91(3.9) 341(3.6)  
Year of Diagnosis 2004–2007 670(28.9) 1833(19.4) < 0.001
2008–2011 864(37.2) 3918(41.4)  
2012–2014 787(33.9) 3711(39.2)  
TNM Stage I 944(40.6) 3520(37.2) < 0.001
II 437(18.8) 2536(26.8)  
III 524(22.6) 1840(19.4)  
IV 280(12.1) 869(9.2)  
Unknown 136(5.9) 697(7.4)  
SEER Stage Localized 1365(58.8) 5366(56.7) < 0.001
Regional 621(26.7) 3015(31.8)  
Distant 299(12.9) 910(9.6)  
Unstaged 36(1.6) 171(1.8)  
Pathological Grade Well differentiated 394(17.0) 1055(11.2) < 0.001
Moderately differentiated 658(28.3) 1484(15.7)  
Poorly differentiated 279(12.0) 524(5.5)  
Undifferentiated 22(1.0) 39(0.4)  
Unknown 968(41.7) 6360(67.2)  
AFP Negative 576(24.8) 2116(22.4) < 0.001
Positive 1324(57.1) 6234(65.9)  
Borderline 12(0.5) 22(0.2)  
Unknown 409(17.6) 1090(11.5)  
Tumor Size <  2 cm 179(7.7) 1227(13.0) < 0.001
≥ 2 cm 1918(82.6) 7386(78.0)  
Unknown 224(9.7) 849(9.0)  
Therapy None 1190(51.3) 6536(69.1) < 0.001
Tumor Destruction 247(10.6) 1251(13.2)  
Surgical Resection 733(31.6) 639(6.8)  
Liver Transplantation 137(5.9) 1022(10.8)  
Unknown 14(0.6) 14(0.1)