Fig. 5

Effect of miR-10a overexpression on hematopoietic stem cell xenotransplantation into NSG mice. CD34⁺ cells were transduced with lentiviral vectors encoding pri-miR-10a and a GFP marker or a control (empty vector), then transplanted into myeloablated mice. a After 12 weeks, the bone marrows were harvested and differentiation marker expression on human transduced cells was assessed by flow cytometry. b Each dot represents the percentage of positive cells observed in one mouse, among GFP⁺ cells for CD34, CD38, CD33 and CD36. Results of 3 independent experiments are grouped