From: Ixazomib in combination with carboplatin in pretreated women with advanced triple-negative breast cancer, a phase I/II trial of the AGMT (AGMT MBC-10 trial)
Dose level
Ixazomib
orally on days 1, 8, 15
every 4Â weeks
Carboplatin
i.v. on days 1,8 and 15
1
3Â mg
AUC 1.5
2
AUC 2
3
4Â mg
4
AUC 2.5