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Table 5 Survival analysis of patients with chronic obstructive pulmonary disease (COPD) according to airway obstruction

From: Effect of COPD on symptoms, quality of life and prognosis in patients with advanced non-small cell lung cancer

Variables Univariate analysis Multivariate analysis
HR (95% CI) p-value HR (95% CI) p-value
COPD
 (−) 1   1  
 (+) 1.42 (1.02–1.98) 0.036 0.94 (0.64–1.38) 0.763
Stage
 Stage 3 1   1  
 Stage 4 1.68 (1.14–2.48) 0.009 2.03 (1.36–3.01) 0.001
Age
  < 65 1   1  
  ≥ 65 1.76 (1.22–2.53) 0.003 1.87 (1.28–2.73) 0.001
Sex
 Female 1   1  
 Male 2.00 (1.28–3.12) 0.002 2.26 (1.41–3.62) 0.001
BMI
  < 23 1    
  ≥ 23 0.78 (0.56–1.09) 0.143   
Comorbidity
 No 1    
 Yes 1.39 (0.99–1.93) 0.054   
History of smoking
 Never smoker 1    
 Former or current smoker 1.51 (0.99–2.29) 0.056   
Symptom
 No 1    
 Yes 1.55 (0.97–2.49) 0.070   
FEV1
  ≥ 60 1   1  
  < 60 1.46 (1.02–2.09) 0.041 1.42 (0.96–2.11) 0.084
  1. COPD chronic obstructive pulmonary disease, BMI body mass index, FEV1 forced expiratory volume in 1 s, HR hazard ratio, CI confidence interval
  2. The Cox proportional hazards modeling technique was used