Table 4 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ)-C30 scores of patients with chronic obstructive pulmonary disease (COPD) according to airway obstruction
Variables | GOLD grade 1 (n = 35) | GOLD grade 2 (n = 103) | GOLD grade 3 (n = 24) | GOLD grade 4 (n = 8) | p value |
|---|---|---|---|---|---|
Global health status/QoL | 50.5 ± 26.3 | 50.2 ± 23.0 | 41.0 ± 19.0 | 30.2 ± 26.7 | 0.049 |
Functional scales | |||||
Physical functioning | 83.4 ± 17.1 | 75.4 ± 22.7 | 66.7 ± 24.4 | 53.3 ± 30.4 | 0.004 |
Role functioning | 79.5 ± 31.3 | 75.9 ± 24.2 | 69.4 ± 33.9 | 54.2 ± 39.6 | 0.132 |
Emotional functioning | 75.0 ± 26.2 | 76.4 ± 25.0 | 78.5 ± 21.8 | 70.8 ± 32.1 | 0.970 |
Cognitive functioning | 87.1 ± 21.4 | 79.0 ± 25.1 | 77.8 ± 22.3 | 75.0 ± 21.8 | 0.123 |
Social functioning | 72.4 ± 28.9 | 68.1 ± 26.4 | 68.1 ± 26.4 | 60.4 ± 33.3 | 0.646 |
Symptom scales/items | |||||
Fatigue | 25.1 ± 24.6 | 34.5 ± 22.8 | 40.7 ± 24.7 | 47.2 ± 31.3 | 0.011 |
Nausea and vomiting | 9.5 ± 23.3 | 9.2 ± 15.8 | 1.4 ± 4.7 | 8.3 ± 23.6 | 0.059 |
Pain | 18.6 ± 30.2 | 22.0 ± 26.8 | 20.1 ± 26.5 | 25.0 ± 38.8 | 0.622 |
Dyspnea | 20.0 ± 24.5 | 33.7 ± 31.8 | 44.4 ± 36.3 | 54.2 ± 35.4 | 0.010 |
Insomnia | 24.8 ± 31.7 | 27.2 ± 29.4 | 36.1 ± 31.0 | 37.5 ± 37.5 | 0.352 |
Appetite loss | 27.6 ± 36.6 | 30.4 ± 32.0 | 31.9 ± 36.1 | 45.8 ± 43.4 | 0.621 |
Constipation | 14.3 ± 24.6 | 16.2 ± 26.8 | 19.4 ± 31.0 | 41.7 ± 49.6 | 0.435 |
Diarrhea | 7.6 ± 18.2 | 7.8 ± 20.5 | 6.9 ± 17.0 | 4.2 ± 11.8 | 0.988 |
Financial difficulties | 25.7 ± 31.4 | 32.7 ± 29.9 | 40.3 ± 34.0 | 37.5 ± 33.0 | 0.320 |