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Table 2 Symptoms of patients with and without chronic obstructive pulmonary disease (COPD)

From: Effect of COPD on symptoms, quality of life and prognosis in patients with advanced non-small cell lung cancer

Variables Total
(n = 337)
COPD
(n = 170)
Non-COPD
(n = 167)
p value
Respiratory
 Cough 212 (62.9) 117 (68.8) 95 (56.9) 0.025
 Sputum 173 (51.3) 99 (58.2) 74 (44.3) 0.012
 Chest pain 126 (37.4) 70 (41.2) 56 (33.5) 0.177
 Hoarseness 67 (19.9) 39 (22.9) 28 (16.8) 0.173
 Wheezing or stridor 88 (26.1) 49 (28.8) 39 (23.4) 0.267
 Dyspnea 93 (27.6) 60 (35.3) 33 (19.8) 0.002
 Hemoptysis 24 (7.1) 17 (10.0) 7 (4.2) 0.055
General
 Fatigue 144 (42.7) 74 (43.5) 70 (41.9) 0.826
 Weight loss 121 (35.9) 64 (37.7) 57 (34.1) 0.570
 Pain 80 (23.7) 38 (22.4) 42 (25.2) 0.609
 General weakness 112 (33.2) 60 (35.3) 52 (31.1) 0.421
 Poor oral intake 113 (33.5) 63 (37.1) 50 (29.9) 0.204
 Fever 18 (5.3) 8 (4.7) 10 (6.0) 0.636
Number of symptoms
 Mean(±SD) 0.8(±0.7) 1.0(±0.7) 0.5(±0.6) 1.332E-13
 0 55 (16.3) 17 (10.0) 38 (22.8) 0.004
 1 60 (17.8) 29 (17.1) 31 (18.56)  
  ≥ 2 222 (65.9) 124 (72.9) 98 (58.7)  
  1. Data are mean (±SD) and n (%). COPD, chronic obstructive pulmonary disease
  2. For continuous variables, Student’s t test was used; for univariate analysis, the chi-square test was used