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Table 2 Symptoms of patients with and without chronic obstructive pulmonary disease (COPD)

From: Effect of COPD on symptoms, quality of life and prognosis in patients with advanced non-small cell lung cancer

Variables

Total

(n = 337)

COPD

(n = 170)

Non-COPD

(n = 167)

p value

Respiratory

 Cough

212 (62.9)

117 (68.8)

95 (56.9)

0.025

 Sputum

173 (51.3)

99 (58.2)

74 (44.3)

0.012

 Chest pain

126 (37.4)

70 (41.2)

56 (33.5)

0.177

 Hoarseness

67 (19.9)

39 (22.9)

28 (16.8)

0.173

 Wheezing or stridor

88 (26.1)

49 (28.8)

39 (23.4)

0.267

 Dyspnea

93 (27.6)

60 (35.3)

33 (19.8)

0.002

 Hemoptysis

24 (7.1)

17 (10.0)

7 (4.2)

0.055

General

 Fatigue

144 (42.7)

74 (43.5)

70 (41.9)

0.826

 Weight loss

121 (35.9)

64 (37.7)

57 (34.1)

0.570

 Pain

80 (23.7)

38 (22.4)

42 (25.2)

0.609

 General weakness

112 (33.2)

60 (35.3)

52 (31.1)

0.421

 Poor oral intake

113 (33.5)

63 (37.1)

50 (29.9)

0.204

 Fever

18 (5.3)

8 (4.7)

10 (6.0)

0.636

Number of symptoms

 Mean(±SD)

0.8(±0.7)

1.0(±0.7)

0.5(±0.6)

1.332E-13

 0

55 (16.3)

17 (10.0)

38 (22.8)

0.004

 1

60 (17.8)

29 (17.1)

31 (18.56)

 

  ≥ 2

222 (65.9)

124 (72.9)

98 (58.7)

 
  1. Data are mean (±SD) and n (%). COPD, chronic obstructive pulmonary disease
  2. For continuous variables, Student’s t test was used; for univariate analysis, the chi-square test was used