Table 3 Univariate analysis of prognostic factors for overall survival in resected pancreatic ductal adenocarcinoma
Variable | Mean OS [months] | 95% CI | Median OS [months] | p value | |||
|---|---|---|---|---|---|---|---|
Total | 27.0 | 22.3 | – | 31.6 | 21.4 | ||
Sex | female | 23.1 | 17.7 | – | 28.5 | 16.3 | 0.122 |
male | 30.2 | 22.5 | – | 37.9 | 34.2 | ||
Age | ≤60 years | 29.4 | 21.6 | – | 37.1 | 21.4 | 0.398 |
> 60 years | 25.4 | 20.1 | – | 30.8 | 20.2 | ||
T status | T1–2 | 26.2 | 15.2 | – | 37.2 | 17.0 | 0.969 |
T3–4 | 26.8 | 21.8 | – | 31.9 | 22.2 | ||
N status | N0 | 33.1 | 26.1 | – | 40.2 | 34.2 | 0.021 |
N1 | 21.5 | 16.1 | – | 26.8 | 16.3 | ||
Tumor grading | G1–2 | 28.1 | 21.3 | – | 34.9 | 36.8 | 0.228 |
G3 | 25.3 | 19.6 | – | 31.0 | 16.7 | ||
Residual tumor | R0 | 31.4 | 24.0 | – | 38.8 | 34.2 | 0.052 |
R1 | 19.8 | 15.7 | – | 23.9 | 16.7 | ||
ERβ expression | negative | 30.9 | 25.2 | – | 36.7 | 34.2 | 0.009 |
positive | 16.6 | 12.7 | – | 20.4 | 12.2 | ||
Perioperative | CRT/CTX | 25.5 | 18.5 | 32.5 | 17.4 | 0.800 | |
therapy | none | 27.2 | 21.5 | 32.9 | 21.4 | ||