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Table 2 Differential Diagnosis Between SPC and GC with HM

From: Synchronous cancers of gallbladder carcinoma and combined hepatocellular cholangiocarcinoma: an unusual case and literature review

 

SPC

GC with HM

Incidences

Rare, 8 cases

Geography/ethnicity (1.1~ 27/105)

Gender

Major in F (F/M = 2/1)

Major in F (F/M = 2~ 6/1)

Age(yrs)

Old age (Mean = 68.8)

Old age (Mean = 67)

HBV/HCV

Partial patients

Not

Gallbladder stones

50%

~ 85%

AFP

Elevated in partial patients

Not

CEA

Elevated

Elevated

CA19–9

Elevated

Elevated

Number of liver masses

Simple or multiple

Multiple

Location of liver masses

Any segments in the liver

Adjacent to the gallbladder

Invasion of GC

Not found

Presentation

Imaging manifestation

Hypovascular or hypervascular

Hypovascular

  1. SPC synchronous primary cancers, GC gallbladder adenocarcinoma, HM hepatic metastasis, M male, F female, HBV hepatitis B virus, HCV hepatitis C virus, AFP alpha-fetoprotein, CEA carcinoembryonic antigen, CA19–9 carbohydrate antigen 19–9