Fig. 7From: The small organic molecule C19 binds and strengthens the KRAS4b-PDEδ complex and inhibits growth of colorectal cancer cells in vitro and in vivoC19 prevents phosphorylation of Erk and Akt in vitro and in vivo. a Cell lysates and (b) tumor lysates were analyzed by Western blot for phosphorylation levels of ERK (p-Erk) and Akt (P-Akt). Total Erk, total Akt and β-actin served as loading control. Representative blots of three independent experiments are shownBack to article page