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Fig. 6 | BMC Cancer

Fig. 6

From: Discovery of a diagnostic biomarker for colon cancer through proteomic profiling of small extracellular vesicles

Fig. 6

Diagnostic value of TSPAN1-positive EVs in plasma. a TSPAN1-positive small-EVs in plasma were captured using the coated anti-CD63 antibody and detected using the anti-TSPAN1 antibody. b TSPAN1-positive small-EVs were validated in the plasma of colon cancer patients (CC, n = 37) and healthy controls (HC, n = 30). Significance was analyzed using the Mann-Whitney test. ****p < 0.0001. c ROCs for differentiating between CC patients and HCs were analyzed. The AUC, sensitivity, and specificity for TSPAN1 are shown

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