Table 1 IC50 values of SCH772984 and MEK162 in parental and resistant cells
| Â | IC50 MEK162 (nM) | RI | IC50 SCH772984 (nM) | RI |
|---|---|---|---|---|
H727 | 115 | – | 135 | – |
H727-MEK | > 1000 | >  9 | > 1000 | >  9 |
H727-SCH | > 1000 | >  9 | > 1000 | >  9 |
| Â | IC50 MEK162 (nM) | RI | IC50 SCH772984 (nM) | RI |
|---|---|---|---|---|
H727 | 115 | – | 135 | – |
H727-MEK | > 1000 | >  9 | > 1000 | >  9 |
H727-SCH | > 1000 | >  9 | > 1000 | >  9 |