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Table 1 Anticancer drugs have different effects on DHA’s cytotoxicity in cancer cells

From: Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1

MTS assay Cytotoxicity enhanced Cytotoxicity attenuated Cytotoxicity unchanged
Initial screen 48 32 21
Validationa 21 20 4
  1. aOnly 45 drugs available for the validation screen
  2. MDA-MB-231 cells were treated with individual drugs (101 anticancer drugs, the NCI Oncology Set IV) at IC25 and IC50 drug concentrations, and DHA (at 50 μM for initial screen and 25, 50, and 100 μM for validation) for 48 h. Cell viability was determined by MTS assay