Fig. 5

Sorafenib and DHA act in synergy to suppress MDA-MB-231 cell viability. a Cells were treated with increasing concentrations of Sorafenib and DHA at a fixed ratio of 1:100, determined by the IC₅₀ values of each compound added to cells alone. Cell viability was analyzed using the MTS assay. b An isobologram was plotted using the IC₅₀ values of Sorafenib and DHA alone on the Y- and X-axes, respectively. Experimentally derived values from combination treatment lying beneath the addition line indicate a synergistic interaction (n = 3)