Fig. 1

ATP2B4 gene expression is downregulated in breast carcinomas compared to normal breast tissue. ATP2B1, ATP2B2 and ATP2B4 gene expression data were obtained from the Oncomine database [35]. a: Relative gene expression of normal (n = 4) vs. invasive breast carcinoma (n = 154) tissues from the „Gluck breast” study [76]. ATP2B1: fold change: 1.069; P-value: 0.358; t-test: 0.396. ATP2B2: fold change: 1.919; P-value: 0.155; t-test: 1.215. ATP2B4: fold change: − 2.606; P-value: 0.013; t-test: − 3.974. b: Relative gene expression of normal (n = 61) vs. invasive ductal breast carcinoma (n = 389) tissues from „TCGA breast” study (2011). ATP2B1: fold change: − 1.093; P-value: 0.096; t-test: -1.314. ATP2B2: fold change: 1.095; P-value: 0.067; t-test: 1.513. ATP2B4: fold change: − 2.161; P-value: 7.79 e-15; t-test: − 9.455 c: Relative gene expression of normal (n = 144) vs. invasive ductal breast carcinoma (n = 1556) tissues from „Curtis breast” study [77]. ATP2B1: fold change: − 1.013; P-value: 0.158; t-test: -1.006. ATP2B2: fold change: 1.029; P-value: 0.001; t-test: 3.040. ATP2B4: fold change: − 2.061; P-value: 5.33 e-40; t-test: − 17.593