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Table 1 Five case reports of lung squamous cell carcinoma with intraocular metastasis

From: Lung squamous cell carcinoma with solitary ocular metastasis and its successful treatment with thoracic surgery and chemotherapy: an interesting and rare case report

Age/s Sex

Lung cancer location

Ocular involvement

Tumor location

Symptom

Ocular symptoms are the initial symptoms

Other metastatic sites

Systemic treatment/Response

Ocular treatment/Response

OS (months)

First author/Year

Thoracic operation

managed by MDT

52/M

Left upper lobe

Retina

LE&RE

Decreased visual acuity

Y

Brain, meninges, lymph nodes, liver, adrenal glands, spleen, kidney, lungs, heart

NA

NA

2

Ronald Klein/1977

N

N

72/F

Right lower lobe

Iris

LE

Ocular pain, blurred vision

N

Brain

Chemo (vindesine, cisplatin)/PR

Radio /CR

6.3

Akio Hiraki/1998

N

N

46/M

Right upper lobe

Choroid

LE

Reduction in vision with concomitant blurriness

Y

Adrenal, brain, bone

Chemo/NA

Radio/NA

NA

Christos Asteriou/2010

N

N

35/F

Right upper lobe

Choroid

LE

Pain, blurred vision

Y

None

Chemo(paclitaxel, cisplatin)/NA

Radio/SD

NA

Archana Prathipati/2016

N

N

54/M

NA

Retina

LE

Blurred vision

N

Brain

Chemo(paclitaxel, carboplatin)/PR; Chemo(docetaxel, carboplatin )/PR

None

NA (follow-up 9 months)

Ozgur Yalcinbayir/2017

N

N