Prognostic factors for survival after curative resection of gastric mixed adenoneuroendocrine carcinoma: a series of 80 patients

Table 4 Univariable and multivariable Cox regression analyses of RFS

	Univariable			Multivariable
	n	recurrence	P value	HR	95% CI	P value
Age(year)			0.663
< 65	37	22
≥ 65	43	17
Gender			0.915
Male	61	29
Female	19	10
ASA score			0.377
1	42	18
2	30	17
≥ 3	8	4
Tumor size (cm)			0.555
< 5	46	22
≥ 5	34	17
Tumor location			0.119
Upper	38	18
Middle	12	3
Lower	20	11
Diffuse	10	7
T stage			0.08
T1 + T2	13	4
T3	37	16
T4	30	19
N stage			0.182
N0	16	5
N1	64	34
TNM stage			0.249
I-II	16	6
III	67	33
Operation types			0.381
Total gastrectomy	56	25
Distal gastrectomy	24	14
Surgical method			0.162
Open	25	14
Laparoscopic	55	25
Complication			0.081
Yes	13	7
No	67	32
Ki-67positive index (%)			0.026	1.979	1.012–3.870	0.046
< 60	34	14
≥ 60	46	25
tumor component in the primary tumor			0.751
AC higher	34	16
NEC higher	46	23
Tumor domination			0.025	1.993	1.016–3.909	0.045
AC dominant type	36	13
NEC dominant type	44	26
Adjuvant chemotherapy			0.807
Yes	50	27
No	30	12

ISSN: 1471-2407