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Table 3 Multivariate Cox-regression analysis of the prognostic impact on metachronous distant metastasis

From: Genetic and immunological biomarkers predict metastatic disease recurrence in stage III colon cancer

 

p

HR

95% CI

Lower

Upper

KRAS (mutated)

0.008

3.21

1.36

7.59

BRAF (mutated)

0.106

5.45

0.67

42.42

MMR (MSI-H)

0.777

0.81

0.19

3.50

Osteopontin (continuously)

0.852

1.00

0.99

1.00

SASH1 (continuously)

0.103

3.01

0.80

11.31

MACC1 (continuously)

0.980

0.99

0.90

1.11

CD3 (continuously)

0.109

1.01

0.99

1.01

CD8 (continuously)

0.009

0.99

0.97

0.99

  1. CI confidence interval, HR hazard ratio, MMR mismatch repair, MSI-H high-grade microsatellite instability