Table 5 Surgical outcomes among patients undergoing radical cystectomy by antidepressant use before cancer diagnosis
Surgical outcome | Non-users | AD users |
|---|---|---|
Length of stay (LOS) | ||
Days admitted, median (IQR) | 10 (7–13) | 9 (8–13) |
Unadjusted ratio of median LOS (95% CI) | Ref. | 1.03 (0.95–1.13) |
Adjusteda ratio of median LOS (95% CI) | Ref. | 1.02 (0.93–1.12) |
30-day acute readmission | ||
Total, n | 2241 | 151 |
Readmitted, n | 747 | 62 |
Cumulative incidence, % (95% CI) | 33.4 (31.4–35.3) | 41.1 (33.2–48.8) |
Unadjusted HR (95% CI) | Ref. | 1.36 (1.08–1.71) |
Adjusteda HR (95% CI) | Ref. | 1.33 (1.05–1.67) |
90-day postoperative procedure | ||
Total, n | 2370 | 162 |
Procedures, n | 908 | 72 |
Cumulative incidence, % (95% CI) | 38.3 (36.4–40.3) | 44.4 (36.7–51.9) |
Unadjusted HR (95% CI) | Ref. | 1.19 (0.93–1.51) |
Adjusted* HR (95% CI) | Ref. | 1.18 (0.93–1.51) |
One-year all-cause mortality | ||
Total, n | 2370 | 162 |
Deaths, n | 330 | 24 |
Cumulative incidence, % (95% CI) | 14.4 (13.1–16.0) | 15.0 (10.3–21.6) |
Unadjusted HR (95% CI) | Ref. | 1.05 (0.69–1.58) |
Adjusteda HR (95% CI) | Ref. | 0.96 (0.63–1.46) |
Three-year all-cause mortality | ||
Total, n | 2370 | 162 |
Deaths, n | 650 | 52 |
Cumulative incidence, % (95% CI) | 31.3 (29.3–33.4) | 35.4 (28.1–43.8) |
Unadjusted HR (95% CI) | Ref. | 1.16 (0.88–1.54) |
Adjusteda HR (95% CI) | Ref. | 1.02 (0.77–1.36) |