Table 1 Patient characteristics at diagnosis according to use of antidepressants before cancer diagnosis
Non-users | AD users | |||
|---|---|---|---|---|
n | % | n | % | |
Total | 9348 | 89.7 | 1079 | 10.3 |
Median age (IQR) (years) | 72.5 | 66.0–79.8 | 74.4 | 67.8–82.3 |
Age group (years) | ||||
18–49 | 224 | 2.4 | 22 | 2.0 |
50–59 | 814 | 8.7 | 85 | 7.9 |
60–69 | 2554 | 27.3 | 235 | 21.8 |
70–79 | 3475 | 37.2 | 378 | 35.0 |
80- | 2281 | 24.4 | 3539 | 33.3 |
Sex | ||||
Male | 7036 | 75.3 | 647 | 60.0 |
Female | 2312 | 24.7 | 432 | 40.0 |
Marital status | ||||
Married | 5549 | 59.4 | 532 | 49.3 |
Widowed | 1836 | 19.6 | 320 | 29.7 |
Divorced | 1233 | 13.2 | 145 | 13.4 |
Never married | 730 | 7.8 | 82 | 7.6 |
Charlson Comorbidity Index score | ||||
Low (0) | 4703 | 50.3 | 334 | 31.0 |
Medium (1–2) | 3124 | 33.4 | 437 | 40.5 |
High (3+) | 1521 | 16.3 | 308 | 28.5 |
Alcohol-related disorders | 191 | 2.0 | 68 | 6.3 |
Year of cancer diagnosis | ||||
2005–2007 | 2563 | 27.4 | 271 | 25.1 |
2008–2010 | 2555 | 27.3 | 283 | 26.2 |
2011–2013 | 2527 | 27.0 | 314 | 29.1 |
2014–2015 | 1703 | 18.2 | 211 | 19.6 |
Stage of cancer at diagnosis | ||||
Non-muscle-invasive (pT1) | 3538 | 37.8 | 423 | 39.2 |
Muscle-invasive (pT2+) | 3854 | 41.2 | 437 | 40.5 |
Missing | 1956 | 20.9 | 219 | 20.3 |
Cystectomy | 2370 | 25.4 | 162 | 15.0 |
Neoadjuvant chemotherapy | 222 | 9.4 | 15 | 9.3 |
Intended curative radiation therapy | 1145 | 12.3 | 114 | 10.6 |