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Table 6 Cox regression model for overall survival in all the patients with EHEs (n = 42)

From: Clinical characteristics of Japanese patients with epithelioid hemangioendothelioma: a multicenter retrospective study

  Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age (years)
 < 55 Ref    Ref   
 ≥ 55 1.249 0.361–4.316 0.725 5.804 0.860–39.176 0.071
Sex
 Female Ref    Ref   
 Male 0.919 0.266–3.175 0.893 1.602 0.336–7.638 0.555
Symptoms
 Absence Ref    Ref   
 Presence 4.643 0.983–21.928 0.053 3.973 0.774–20.384 0.098
Tumor diameter (cm)
 ≤ 3.0 Ref    Ref   
 > 3.0 5.842 0.739–46.182 0.094 13.327 1.012–175.520 0.049
Organ involvement
 Single Ref    Ref   
 Multiple 0.721 0.209–2.493 0.606 0.311 0.065–1.479 0.142
Ki-67 labeling indexa
 ≤ 10 Ref      
 > 10 7.526 0.770–73.558 0.083    
  1. HR hazard ratio, CI confidence interval, Ref reference
  2. a The Ki-67 labeling index was not evaluated by multivariate analysis because its value in 24 of the 42 patients was unknown