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Table 6 Cox regression model for overall survival in all the patients with EHEs (n = 42)

From: Clinical characteristics of Japanese patients with epithelioid hemangioendothelioma: a multicenter retrospective study

 

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Age (years)

 < 55

Ref

  

Ref

  

 ≥ 55

1.249

0.361–4.316

0.725

5.804

0.860–39.176

0.071

Sex

 Female

Ref

  

Ref

  

 Male

0.919

0.266–3.175

0.893

1.602

0.336–7.638

0.555

Symptoms

 Absence

Ref

  

Ref

  

 Presence

4.643

0.983–21.928

0.053

3.973

0.774–20.384

0.098

Tumor diameter (cm)

 ≤ 3.0

Ref

  

Ref

  

 > 3.0

5.842

0.739–46.182

0.094

13.327

1.012–175.520

0.049

Organ involvement

 Single

Ref

  

Ref

  

 Multiple

0.721

0.209–2.493

0.606

0.311

0.065–1.479

0.142

Ki-67 labeling indexa

 ≤ 10

Ref

     

 > 10

7.526

0.770–73.558

0.083

   
  1. HR hazard ratio, CI confidence interval, Ref reference
  2. a The Ki-67 labeling index was not evaluated by multivariate analysis because its value in 24 of the 42 patients was unknown