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Table 5 Systemic chemotherapy for the patients with EHEs

From: Clinical characteristics of Japanese patients with epithelioid hemangioendothelioma: a multicenter retrospective study

Systemic chemotherapy regimen No. (%) Individual response
1st-line treatment 10 (100)  
 Carboplatin + paclitaxel + bevacizumab 3   PR, SD, PD
 Paclitaxel 2   SD, SD
 Pazopanib 2   SD, SD
 Bevacizumab 1   SD
 Streptozocin 1   NE
 Cisplatin + epirubicin + bevacizumab 1   PD
2nd-line treatment 4 (40)  
 Carboplatin + pemetrexed + bevacizumab 1   PR
 Thalidomide 1   PD
 Irinotecan 1   SD
 Interleukin-2 1   SD
3rd-line treatment 3 (30)  
 Adriamycin 1   SD
 Paclitaxel 1   SD
 Pemetrexed + bevacizumab 1   SD
4th-line treatment 1 (10)  
 Investigational drug 1   SD
5th-line treatment 1 (10)  
 Investigational drug 1   SD
  1. PR partial response, SD stable disease, PD progressive disease, NE not evaluated