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Table 5 Systemic chemotherapy for the patients with EHEs

From: Clinical characteristics of Japanese patients with epithelioid hemangioendothelioma: a multicenter retrospective study

Systemic chemotherapy regimen

No.

(%)

Individual response

1st-line treatment

10

(100)

 

 Carboplatin + paclitaxel + bevacizumab

3

 

PR, SD, PD

 Paclitaxel

2

 

SD, SD

 Pazopanib

2

 

SD, SD

 Bevacizumab

1

 

SD

 Streptozocin

1

 

NE

 Cisplatin + epirubicin + bevacizumab

1

 

PD

2nd-line treatment

4

(40)

 

 Carboplatin + pemetrexed + bevacizumab

1

 

PR

 Thalidomide

1

 

PD

 Irinotecan

1

 

SD

 Interleukin-2

1

 

SD

3rd-line treatment

3

(30)

 

 Adriamycin

1

 

SD

 Paclitaxel

1

 

SD

 Pemetrexed + bevacizumab

1

 

SD

4th-line treatment

1

(10)

 

 Investigational drug

1

 

SD

5th-line treatment

1

(10)

 

 Investigational drug

1

 

SD

  1. PR partial response, SD stable disease, PD progressive disease, NE not evaluated