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Table 2 The recurrence and pregnancy outcomes of borderline ovarian tumor patients

From: The impact of clinicopathologic and surgical factors on relapse and pregnancy in young patients (≤40 years old) with borderline ovarian tumors

  Recurrence outcome Pregnancy outcome
N recurrence/Total (%) P value Recurrence interval (m, mean) P value N patients achieving/attempting pregnancy (%) P value
FIGO stage Stage I 11/42 (26.2) 0.016 55 0.036 11/16 (68.8) 1.000
≥Stage II 8/12 (66.7)   42   4/6 (66.7)  
Diameter < 10 cm 11/27 (40.7) 0.569 48 0.108 5/11 (45.5) 0.063
≥10 cm 8/27 (29.6)   N/A   10/11 (90.9)  
Histology Serous 15/26 (57.7) 0.003 42 0.007 9/13 (69.2) 0.313
Mucinous 3/25 (12.0)   N/A   6/8 (75.0)  
Othersa 1/3 (33.3)   55   0/1 (0)  
Lesion lateral Unilateralb 12/43 (27.9) 0.038 55 0.011 13/18 (72.2) 0.565
Bilateral 7/11 (63.6)   24   2/4 (50.0)  
Rupture Yes 3/10 (30.0) 1.000 42 0.743 2/4 (50.0) 0.565
No 16/44 (36.4)   55   13/18 (72.2)  
Micropapillary Yes 8/11 (72.7) 0.010 28 0.003 3/4 (75.0) 1.000
No 11/43 (25.6)   36   12/18 (66.7)  
Microinvasion Yes 3/5 (60.0) 0.332 48 0.607 1/1 (100.0) 1.000
No 16/49 (32.7)   55   14/21 (66.7)  
Invasive implants Yes 2/0 (100.0) 0.119 4 0.116 0/0 (0) N/A
No 17/52 (32.7)   48   15/22 (68.2)  
Pelvic lymph node Positive 2/6 (33.3) 1.000 N/A 0.984 0/3 (0) 0.023
Negative 17/48 (35.4)   48   15/19 (78.9)  
Lymphadenectomy Yes 7/26 (26.9) 0.264 55 0.313 6/12 (50.0) 0.074
No 12/28 (42.9)   48   9/10 (90.0)  
Surgery approach Laparoscopy 1/5 (20.0) 0.646 36 0.907 2/3 (66.7) 1.000
Laparotomy 18/49 (36.7)   48   13/19 (68.4)  
Adjuvant chemotherapy Yes 2/4 (50.0) 0.607 8 0.056 0/2 (0)  
No 17/50 (34.0)   55   15/20 (75.0) 0.091
Staging surgery Yes 19/51 (37.3) 0.189 N/A 0.320 14/20 (70.0) 1.000
No 0/3 (0)   N/A   1/2 (50.0)  
Appendectomy Yes 0/5 (0) 0.149 N/A 0.287 1/2 (50.0) 1.000
No 19/49 (38.8)   N/A   14/20 (70.0)  
Fertility sparing surgery (1) Cystectomy 3/5 (60.0) 0.054 36 0.031 1/2 (50.0) 0.855
Bilateral cystectomy 1/2 (50.0)   41   1/1 (100.0)  
Unilateral salpingo-oophorectomy 9/38 (23.7)   55   11/16 (68.8)  
Unilateral salpingo-oophorectomy + contralateral cystectomy 6/9 (66.7)   21   2/3 (66.7)  
Fertility sparing surgery (2)
 Unilateralb Cystectomy 3/5 (60.0) 0.123 36 0.133 1/2 (50.0) 1.000
Unilateral salpingo-oophorectomy 9/38 (23.7)   55   11/16 (68.8)  
 Bilateral Bilateral cystectomy 1/2 (50.0) 1.000 41 0.482 1/1 (100.0) 1.000
Unilateral salpingo-oophorectomy + contralateral cystectomy 6/9 (66.7)   21   2/3 (66.7)  
 Fertility sparing surgery (3) Cystectomy-included 10/16 (62.5) 0.012 27 0.007 4/6 (66.7) 1.000
Adnexectomy 9/38 (23.7)   55   11/16 (68.8)  
  1. aothers included endometroid, serous and mucinous; bunilateral included left and right; FIGO, the International Federation of Gynecology and Obstetrics; N/A, not applicable