Table 2 The recurrence and pregnancy outcomes of borderline ovarian tumor patients
Recurrence outcome | Pregnancy outcome | ||||||
|---|---|---|---|---|---|---|---|
N recurrence/Total (%) | P value | Recurrence interval (m, mean) | P value | N patients achieving/attempting pregnancy (%) | P value | ||
FIGO stage | Stage I | 11/42 (26.2) | 0.016 | 55 | 0.036 | 11/16 (68.8) | 1.000 |
≥Stage II | 8/12 (66.7) | 42 | 4/6 (66.7) | ||||
Diameter | < 10 cm | 11/27 (40.7) | 0.569 | 48 | 0.108 | 5/11 (45.5) | 0.063 |
≥10 cm | 8/27 (29.6) | N/A | 10/11 (90.9) | ||||
Histology | Serous | 15/26 (57.7) | 0.003 | 42 | 0.007 | 9/13 (69.2) | 0.313 |
Mucinous | 3/25 (12.0) | N/A | 6/8 (75.0) | ||||
Othersa | 1/3 (33.3) | 55 | 0/1 (0) | ||||
Lesion lateral | Unilateralb | 12/43 (27.9) | 0.038 | 55 | 0.011 | 13/18 (72.2) | 0.565 |
Bilateral | 7/11 (63.6) | 24 | 2/4 (50.0) | ||||
Rupture | Yes | 3/10 (30.0) | 1.000 | 42 | 0.743 | 2/4 (50.0) | 0.565 |
No | 16/44 (36.4) | 55 | 13/18 (72.2) | ||||
Micropapillary | Yes | 8/11 (72.7) | 0.010 | 28 | 0.003 | 3/4 (75.0) | 1.000 |
No | 11/43 (25.6) | 36 | 12/18 (66.7) | ||||
Microinvasion | Yes | 3/5 (60.0) | 0.332 | 48 | 0.607 | 1/1 (100.0) | 1.000 |
No | 16/49 (32.7) | 55 | 14/21 (66.7) | ||||
Invasive implants | Yes | 2/0 (100.0) | 0.119 | 4 | 0.116 | 0/0 (0) | N/A |
No | 17/52 (32.7) | 48 | 15/22 (68.2) | ||||
Pelvic lymph node | Positive | 2/6 (33.3) | 1.000 | N/A | 0.984 | 0/3 (0) | 0.023 |
Negative | 17/48 (35.4) | 48 | 15/19 (78.9) | ||||
Lymphadenectomy | Yes | 7/26 (26.9) | 0.264 | 55 | 0.313 | 6/12 (50.0) | 0.074 |
No | 12/28 (42.9) | 48 | 9/10 (90.0) | ||||
Surgery approach | Laparoscopy | 1/5 (20.0) | 0.646 | 36 | 0.907 | 2/3 (66.7) | 1.000 |
Laparotomy | 18/49 (36.7) | 48 | 13/19 (68.4) | ||||
Adjuvant chemotherapy | Yes | 2/4 (50.0) | 0.607 | 8 | 0.056 | 0/2 (0) | |
No | 17/50 (34.0) | 55 | 15/20 (75.0) | 0.091 | |||
Staging surgery | Yes | 19/51 (37.3) | 0.189 | N/A | 0.320 | 14/20 (70.0) | 1.000 |
No | 0/3 (0) | N/A | 1/2 (50.0) | ||||
Appendectomy | Yes | 0/5 (0) | 0.149 | N/A | 0.287 | 1/2 (50.0) | 1.000 |
No | 19/49 (38.8) | N/A | 14/20 (70.0) | ||||
Fertility sparing surgery (1) | Cystectomy | 3/5 (60.0) | 0.054 | 36 | 0.031 | 1/2 (50.0) | 0.855 |
Bilateral cystectomy | 1/2 (50.0) | 41 | 1/1 (100.0) | ||||
Unilateral salpingo-oophorectomy | 9/38 (23.7) | 55 | 11/16 (68.8) | ||||
Unilateral salpingo-oophorectomy + contralateral cystectomy | 6/9 (66.7) | 21 | 2/3 (66.7) | ||||
Fertility sparing surgery (2) | |||||||
Unilateralb | Cystectomy | 3/5 (60.0) | 0.123 | 36 | 0.133 | 1/2 (50.0) | 1.000 |
Unilateral salpingo-oophorectomy | 9/38 (23.7) | 55 | 11/16 (68.8) | ||||
Bilateral | Bilateral cystectomy | 1/2 (50.0) | 1.000 | 41 | 0.482 | 1/1 (100.0) | 1.000 |
Unilateral salpingo-oophorectomy + contralateral cystectomy | 6/9 (66.7) | 21 | 2/3 (66.7) | ||||
Fertility sparing surgery (3) | Cystectomy-included | 10/16 (62.5) | 0.012 | 27 | 0.007 | 4/6 (66.7) | 1.000 |
Adnexectomy | 9/38 (23.7) | 55 | 11/16 (68.8) | ||||