βcatenin is a marker of poor clinical characteristics and suppressed immune infiltration in testicular germ cell tumors

Table 3 Patients’ characteristics according to the expression of βcatenin

Variable			βcatenin
	N	Median	interquartile range	p-value	Low		High	p-value
					N	%	N	%
All patients	247	100	150	NA	131	53	116	47
Clinical subtype
Pure seminoma	50	50	100	< 0.0001	42	84	8	16	< 0.0001
Non-seminoma	197	200	115		89	45	108	55
Tumor primary
Testicular/retroperitoneal	245	100	150	0.035	131	53	114	47	0.131
Mediastinal	2	300	N/A		0	0	2	100
IGCCCG risk group
Good	184	100	170	0.033	105	57	79	43	0.030
Intermediate/Poor	63	200	130		26	42	37	58
Number of metastatic sites
0	63	100	100	0.408	32	51	31	49	0.813
1 to 2	142	100	175		75	53	67	47
≥ 3	42	100	142.5		24	57	18	43
Retroperitoneal LN metastases
Absent	72	130	100	0.075	36	50	36	50	0.540
Present	175	100	175		95	54	80	46
Mediastinal LN metastases
Absent	215	100	150	0.598	117	54	98	46	0.260
Present	32	200	168.75		14	44	18	56
Lung metastases
Absent	187	100	150	0.967	98	52	89	48	0.726
Present	60	100	145		33	55	27	45
Liver
Absent	229	100	150	0.243	124	54	105	46	0.212
Present	18	200	107.5		7	39	11	61
Non-pulmonary visceral metastases
Absent	225	100	150	0.891	120	53	105	47	0.765
Present	22	150	150		11	50	11	50
S – stage
0–1	187	100	170	0.035	107	57	80	43	0.020
2–3	60	200	130		24	40	36	60

ISSN: 1471-2407