Skip to main content

Table 1 Patient characteristics at diagnosis; primary hematological treatment

From: Impact of renal impairment on outcomes after autologous stem cell transplantation in multiple myeloma: a multi-center, retrospective cohort study

  Group A (n = 238) Group B (n = 67) Group C (n = 50) p-Value
Characteristics
Sex (% male) 58 54 56 0.368
Age (years) 54 ± 9 56 ± 9 59 ± 9 0.003
Monoclonal heavy chain (%)
 IgG 58 45 48 0.103
 IgA 24 27 8 0.031
 IgM 1 2 0.505
 IgD 1 2 0.505
 IgE 2 0 0.116
 Free LC only 17 27 40 0.001
Kappa LC (%) 57 64 54 0.466
Osteolysis (%) 76 85 76 0.583
Clinical stage (ISS, %)     < 0.001
 I 48 18 14  
 II 33 24 30  
 III 12 51 54  
BM infiltration (%) 46 ± 29 54 ± 29 55 ± 25 0.053
Therapy (%)     0.576
 Immuno-chemotherapy 79 75 74  
 Chemotherapy only 21 25 26  
Time between diagnosis and ASCT (months) 13 ± 18 10 ± 10 9 ± 7 0.145
Primary response (%)     0.607
 CR 16 21 17  
 VGPR 34 24 34  
 PR 44 52 40  
 SD 3 2 6  
 PD 4 2 2  
  1. LC light chain, ISS international staging system, BM bone marrow, CR complete remission, VGPR very good partial remission, PR partial remission, SD stable disease, PD progressive disease
  2. p < 0.05: statistically significant