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Table 1 Genes upregulated only in ID8-KRAS-3D cell culture

From: The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway

Gene symbol

Global normalization

ID8-2D

ID8-3D

ID8-KRAS-2D

ID8-KRAS-3D

Tesc

286

282

347

1191

Ifitm1

 

25

132

668

Sprr2a2

18

14

73

550

Gas6

 

62

28

340

Dusp5

81

91

80

322

Sprr2b

14

14

63

288

Txnip

117

173

75

277

Tgfbi

  

4

156

2610318N02Rik

70

31

38

136

Spink4

 

25

2

131

Cma1

3

2

13

126

Bcam

52

93

39

124

Vldlr

10

12

20

120

C1qtnf1

30

50

25

116

Rgs3

25

39

29

112

  1. The top 15 significantly altered genes were upregulated more than 3-fold compared to 2D culture and had a normalized expression level higher than 100