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Fig. 2 | BMC Cancer

Fig. 2

From: The hypermethylation of p16 gene exon 1 and exon 2: potential biomarkers for colorectal cancer and are associated with cancer pathological staging

Fig. 2

The target CpG islands within p16 gene body were obtained by nested PCR. a The CpG island lying p16 exon 1 (313 bp) and (b) The CpG island lying p16 exon 2 (273 bp) were amplified from genomic DNAs of paired tissues from CRC patients, respectively. M: DL1000 DNA Marker (Takara, Dalian); 1C~4C: colorectal cancer tissues; 1A~4A: adjacent normal tissues to corresponding carcinoma; N: negative control; S1~S3: three specific DNA samples with known methylation levels as controls of methylation detection

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BMC Cancer

ISSN: 1471-2407

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