Age-related microRNAs in older breast cancer patients: biomarker potential and evolution during adjuvant chemotherapy

Table 5 Correlation between microRNAs measured at inclusion

MicroRNA^a	miR-20a	miR-30b	miR-34a	miR-106b	miR-191	miR-301a	miR-320b	miR-374a	miR-378a
miR-20a	_	0.252 (0.0174)	0.271 (0.0103)	0.225 (0.0337)	0.035 (0.7421)	0.320 (0.0022)	−0.270 (0.0106)	0.067 (0.5347)	−0.154 (0.1486)
miR-30b	.	_	−0.081 (0.4512)	−0.237 (0.0254)	0.634 (<.0001)	0.624 (<.0001)	0.352 (0.0007)	0.722 (<.0001)	−0.129 (0.2275)
miR-34a	.	.	_	−0.080 (0.4566)	−0.260 (0.0139)	− 0.172 (0.1070)	−0.076 (0.4766)	− 0.256 (0.0153)	−0.054 (0.6129-)
miR-106b	.	.	.	_	−0.401 (<.0001)	0.143 (0.1812)	−0.635 (<.0001)	−0.273 (0.0096)	− 0.106 (0.3210)
miR-191	.	.	.	.	_	0.544 (<.0001)	0.341 (0.0011)	0.761 (<.0001)	−0.235 (0.0265)
miR-301a	.	.	.	.	.	_	−0.056 (0.6036)	0.549 (<.0001)	−0.138 (0.1982)
miR-320b	.	.	.	.	.	.	_	0.330 (0.0016)	0.234 (0.0270)
miR-374a	.	.	.	.	.	.	.	_	−0.384 (0.0002)

Each cell displays the Spearman’s correlation coefficient, and according p-value in parentheses. Strong and highly significant correlations are marked in bold (r > 0.5 and p < 0.01)
^amiR-34a, miR-320b and miR-378a were previously shown to increase with aging; miR-20a, miR-30b, miR-106b, miR-191, miR-301a and miR-374a were previously shown to decrease with aging

ISSN: 1471-2407