Skip to main content

Table 4 Univariable association of microRNAs with aging biomarkers at inclusion

From: Age-related microRNAs in older breast cancer patients: biomarker potential and evolution during adjuvant chemotherapy

MicroRNAa

Telomere length

IL-6

IL-10

IGF-1

TNFα

MCP-1

RANTES

miR-20a

−0.027 (0.8250)

−0.131 (0.2208)

− 0.141 (0.1979)

−0.045 (0.6762)

− 0.101 (0.3474)

−0.045 (0.6743)

− 0.052 (0.6273)

miR-30b

−0.169 (0.1587)

− 0.268 (0.0111)

−0.166 (0.1291)

0.040 (0.7078)

0.049 (0.6479)

−0.168 (0.1165)

0.057 (0.5987)

miR-34a

−0.233 (0.0509)

0.057 (0.5962)

−0.134 (0.2198)

−0.104 (0.3306)

0.099 (0.3551)

0.184 (0.0835)

−0.018 (0.8669)

miR-106b

0.228 (0.0559)

−0.281 (0.0075)

−0.096 (0.3841)

0.118 (0.2721)

−0.310 (0.0031)

− 0.288 (0.0062)

0.174 (0.1033)

miR-191

0.025 (0.8351)

−0.304 (0.0038)

−0.054 (0.6222)

0.015 (0.8891)

−0.101 (0.3478)

− 0.387 (0.0002)

0.074 (0.4878)

miR-301a

−0.038 (0.7507)

−0.340 (0.0011)

− 0.070 (0.5236)

0.098 (0.3604)

− 0.208 (0.0505)

−0.328 (0.0017)

0.029 (0.7846)

miR-320b

−0.234 (0.0492)

0.132 (0.2166)

0.171 (0.1181)

−0.144 (0.1771)

0.396 (0.0001)

0.252 (0.0171)

0.040 (0.7115)

miR-374a

−0.207 (0.0830)

−0.337 (0.0012)

− 0.248 (0.0221)

0.0003 (0.9777)

− 0.024 (0.8250)

−0.231 (0.0294)

0.192 (0.0713

miR-378a

0.018 (0.8842)

0.302 (0.0040)

0.153 (0.1620)

−0.015 0.8866)

0.151 (0.1568)

0.295 (0.0051)

−0.222 (0.0365)

  1. In each cell are displayed the Spearman’s correlation coefficient, and according p-value in parentheses
  2. p-values < 0.05 are marked in bold
  3. amiR-34a, miR-320b and miR-378a were previously shown to increase with aging; miR-20a, miR-30b, miR-106b, miR-191, miR-301a and miR-374a were previously shown to decrease with aging