Estrogen receptor status
|
177
|
0.090
| | | | | |
Progesterone receptor status
|
177
|
0.176
| | | | | |
Histological grade
|
174
|
0.831
| | | | | |
Ki-67 proliferation index
|
177
|
0.171
| | | | | |
Histological type (lobular/ductal)
|
168
|
0.774
| | | | | |
Lymph nodal status pN+ (vs pN0)
|
169
|
0.000***
|
6.7 (8.4)
|
5.9 (8.0) – 7.5 (8.7)
|
0.002**
|
3.486
|
1.608, 7.555
|
Tumor size TNM stage ≥ pT3 (vs < pT3)
|
172
|
0.000***
|
4.2 (7.9)
|
2.3 (7.5) – 6.2 (8.3)
|
0.001***
|
4.016
|
1.703, 9.468
|
Patient age at diagnosis
|
177
|
0.118
| | | | | |
Menopausal status
|
176
|
0.082
| | | | | |
Cytokeratin 5/14 expression
|
167
|
0.447
| | | | | |
Basal phenotype (CK5/14+, ER-)
|
167
|
0.955
| | | | | |
Total cellular HER3 low (vs high)
|
177
|
0.004**
|
6.3 (8.0)
|
5.3 (7.6) – 7.3 (8.4)
|
0.020*
|
2.305
|
1.143, 4.648
|
Membranous HER3 low (vs high)
|
177
|
0.025*
|
6.6 (7.9)
|
5.6 (7.4) – 7.7 (8.3)
| | | |
Cytoplasmic HER3 low (vs high)
|
177
|
0.010*
|
5.9 (7.8)
|
4.2 (7.4) – 7.6 (8.2)
| | | |
NEDD4–1 expression
|
145
|
0.261
| | | | | |
NRDP1 nuclear expression
|
145
|
0.689
| | | | | |
NRDP1 cytoplasmic expression
|
145
|
0.711
| | | | | |