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Table 3 Univariate and multivariate analysis of clinical factors for OS and PFS

From: Inflammation marker ESR is effective in predicting outcome of diffuse large B-cell lymphoma

Variate

multivariate analysis (OS)

multivariate analysis (PFS)

HR

95% CI

P value

HR

95% CI

P value

Non-GCB

0.746

0.299

1.862

0.531

1.630

1.377

2.050

0.076

Myc positivity

1.629

1.057

3.291

< 0.001

1.650

1.227

2.540

< 0.001

B symptom

1.509

1.235

2.104

0.088

0.710

0.425

1.184

0.190

ECOG PS ≥ 2

0.708

0.568

1.015

0.528

0.937

0.521

1.687

0.829

ENI ≥ 2

0.494

0.195

1.251

0.137

1.623

1.236

2.760

0.004

Stage III-IV

1.057

0.534

1.447

0.521

0.768

0.451

1.309

0.333

Elevated LDH

1.891

1.221

2.178

0.094

1.774

1.437

2.371

0.079

IPI 3–5

2.070

1.088

2.550

0.046

2.071

1.066

3.025

0.032

ESR ≥ 37.5 mm/hour

1.897

1.180

2.950

0.037

1.713

1.090

2.261

0.043

  1. Abbreviations: ECOG PS: performance status of Eastern Cooperative Oncology Group; ENI: extranodal involvement; ESR: erythrocyte sedimentation rate; GCB: germinal-center B-cell type; LDH: lactate dehydrogenase; IPI: International Prognostic Index; OS: overall survival; PFS: Progression-free survival
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BMC Cancer

ISSN: 1471-2407

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