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Table 2 Univariate analysis of clinicopathological parameters and inflammatory biomarkers influencing prognosis

From: High postoperative monocyte indicates inferior Clinicopathological characteristics and worse prognosis in lung adenocarcinoma or squamous cell carcinoma after lobectomy

Category Variables Disease-free survival Overall survival
HR (95% CI) P a HR (95% CI) P a
Gender Male Reference   Reference  
Female 0.963(0.716–1.295) 0.801 0.841(0.581–1.216) 0.358
Age Per year 1.008(0.993–1.022) 0.311 1.023(1.004–1.042) 0.017
Smoking history Yes Reference   Reference  
No 1.009(0.756–1.348) 0.950 0.838(0.585–1.202) 0.337
Location Left superior Reference   Reference  
Left inferior 0.989(0.634–1.545) 0.962 1.492(0.870–2.560) 0.146
Right superior 0.875(0.604–1.267) 0.479 1.205(0.758–1.916) 0.431
Right middle 1.263(0.785–2.031) 0.335 1.486(0.817–2.700) 0.194
Right inferior 0.655(0.410–1.047) 0.077 0.899(0.506–1.596) 0.715
Procedure VATS Reference   Reference  
Thoracotomy 1.455(1.093–1.937) 0.010 1.760(1.236–2.505) 0.002
T stage T1 Reference   Reference  
T2 1.219(0.833–1.783) 0.309 1.268(0.775–2.072) 0.344
T3 1.559(0.945–2.573) 0.082 2.453(1.361–4.421) 0.003
T4 1.376(0.609–3.111) 0.443 1.602(0.601–4.271) 0.346
N stage N0 Reference   Reference  
N1 2.467(1.695–3.592) < 0.001 2.869(1.833–4.491) < 0.001
N2 3.349(2.414–4.647) < 0.001 3.442(2.306–5.139) < 0.001
Stage I Reference   Reference  
II 1.847(1.273–2.679) 0.001 2.342(1.460–3.757) < 0.001
IIIA 3.163(2.260–4.428) < 0.001 4.078(2.658–6.258) < 0.001
Histological type Squamous carcinoma Reference   Reference  
Adenocarcinoma 2.994(1.418–6.113) 0.014 1.465(0.712–3.018) 0.300
Differentiation Well Reference   Reference  
Moderate 6.446(0.899–46.191) 0.064 3.869(0.538–27.831) 0.179
Poor 7.172(0.996–51.643) 0.050 4.340(0.599–31.455) 0.146
Preoperative monocyte < 0.375 Reference   Reference  
≥0.375 1.391(1.047–1.849) 0.023 1.490(1.053–2.109) 0.024
Postoperative monocyte <0.845 Reference   Reference  
≥0.845 3.974(2.956–5.342) < 0.001 3.826(2.662–5.499) < 0.001
  1. T stage tumor, N stage node, VATS Video-assistant thoracoscopic surgery, HR hazard ratio, CI confidence interval
  2. aP value of univariate analysis. P < 0.05 was considered statistically significant
  3. The bold data means the data has statistically significance