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Table 4 Overall analysis of miR-20a expression association with clinicopathological characteristics

From: MiR-20a, a novel promising biomarker to predict prognosis in human cancer: a meta-analysis

Clinicopathological parameters No. of studies No. of patients Pooled OR (95%CI) Heterogeneity
Fixed Random I2 p-value
Gender (male vs. female) 7 1103 0.69(0.51,0.92) 0.74(0.50,1.09) 30.70% 0.194
Age (≥60 vs < 60 years) 3 202 1.44(0.81,2.55) 1.44(0.81,2.57) 0.00% 0.373
Tumor Size (≥5 vs < 5 cm) 4 422 0.76(0.51,1.12) 0.77(0.44,1.36) 49.20% 0.116
Lymph node metastasis (absent vs.present) 3 260 1.11(0.68,1.81) 1.03(0.48,2.21) 54.30% 0.112
TNM stage(III + IV vs. I + II) 5 467 0.96(0.66,1.41) 1.15(0.51,2.58) 74.40% 0.004
Differentiation (poor vs. others) 6 951 1.50(1.06,2.13) 1.34(0.73,2.44) 59.10% 0.032
  1. Abbreviations: 95%CI 95% confidence interval, Fixed Fixed effects model, OR Odds ratio, Random Random pooling model