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Table 2 Association between miR-20a expression levels and overall survivals

From: MiR-20a, a novel promising biomarker to predict prognosis in human cancer: a meta-analysis

  No. of studies No. of patients Pooled HR(95%CI) Meta regression Heterogeneity
Fixed Random p-value I2 p-value
Overall 10 1497 1.26(1.06,1.50) 0.99(0.56,1.75)   89.30% 0.000
Population 0.894   
 Chinese 9 1408 1.31(1.10,1.56) 1.09(0.60,1.96)   89.80% 0.000
 Italian 1 89 0.38(0.14,1.00) 0.38(0.14,1.00)  
Sample Size 0.405   
  ≥ 150 3 892 1.77(1.34,2.34) 1.54(0.67,3.54)   84.00% 0.000
  < 150 7 605 1.02(0.82,1.27) 0.82(0.37,1.79)   90.40% 0.000
NOS Scores 0.829   
  ≥ 8 7 1152 1.51(1.24,1.83) 1.19(0.67,2.13)   86.20% 0.000
  < 8 3 345 0.59(0.40,0.88) 0.67(0.17,2.57)   91.50% 0.000
Specimen 0.621   
 blood 3 316 1.93(1.54,2.41) 1.93(1.54,2.41)   0.00% 0.878
 tissues 5 1181 0.69(0.53,0.90) 0.73(0.33,1.62)   88.30% 0.000
Tumor Category 0.350   
 Gastrointestinal cancer 4 769 1.85(1.43,2.40) 1.85(1.43,2.40)   0.00% 0.402
 Non-gastrointestinal cancer 6 728 0.93(0.74,1.17) 0.65(0.26,1.61)   92.50% 0.000
  1. Abbreviations: 95%CI 95% confidence interval, Fixed Fixed effects model, HR hazard ratio, NOS Newcastle-Ottawa scale scores, Random Random pooling model