From: MiR-20a, a novel promising biomarker to predict prognosis in human cancer: a meta-analysis
 | No. of studies | No. of patients | Pooled HR(95%CI) | Meta regression | Heterogeneity | ||
---|---|---|---|---|---|---|---|
Fixed | Random | p-value | I2 | p-value | |||
Overall | 10 | 1497 | 1.26(1.06,1.50) | 0.99(0.56,1.75) | Â | 89.30% | 0.000 |
Population | 0.894 | Â | Â | ||||
 Chinese | 9 | 1408 | 1.31(1.10,1.56) | 1.09(0.60,1.96) |  | 89.80% | 0.000 |
 Italian | 1 | 89 | 0.38(0.14,1.00) | 0.38(0.14,1.00) |  | – | – |
Sample Size | 0.405 | Â | Â | ||||
  ≥ 150 | 3 | 892 | 1.77(1.34,2.34) | 1.54(0.67,3.54) |  | 84.00% | 0.000 |
  < 150 | 7 | 605 | 1.02(0.82,1.27) | 0.82(0.37,1.79) |  | 90.40% | 0.000 |
NOS Scores | 0.829 | Â | Â | ||||
  ≥ 8 | 7 | 1152 | 1.51(1.24,1.83) | 1.19(0.67,2.13) |  | 86.20% | 0.000 |
  < 8 | 3 | 345 | 0.59(0.40,0.88) | 0.67(0.17,2.57) |  | 91.50% | 0.000 |
Specimen | 0.621 | Â | Â | ||||
 blood | 3 | 316 | 1.93(1.54,2.41) | 1.93(1.54,2.41) |  | 0.00% | 0.878 |
 tissues | 5 | 1181 | 0.69(0.53,0.90) | 0.73(0.33,1.62) |  | 88.30% | 0.000 |
Tumor Category | 0.350 | Â | Â | ||||
 Gastrointestinal cancer | 4 | 769 | 1.85(1.43,2.40) | 1.85(1.43,2.40) |  | 0.00% | 0.402 |
 Non-gastrointestinal cancer | 6 | 728 | 0.93(0.74,1.17) | 0.65(0.26,1.61) |  | 92.50% | 0.000 |