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Table 2 Association between miR-20a expression levels and overall survivals

From: MiR-20a, a novel promising biomarker to predict prognosis in human cancer: a meta-analysis

 

No. of studies

No. of patients

Pooled HR(95%CI)

Meta regression

Heterogeneity

Fixed

Random

p-value

I2

p-value

Overall

10

1497

1.26(1.06,1.50)

0.99(0.56,1.75)

 

89.30%

0.000

Population

0.894

  

 Chinese

9

1408

1.31(1.10,1.56)

1.09(0.60,1.96)

 

89.80%

0.000

 Italian

1

89

0.38(0.14,1.00)

0.38(0.14,1.00)

 

–

–

Sample Size

0.405

  

  ≥ 150

3

892

1.77(1.34,2.34)

1.54(0.67,3.54)

 

84.00%

0.000

  < 150

7

605

1.02(0.82,1.27)

0.82(0.37,1.79)

 

90.40%

0.000

NOS Scores

0.829

  

  ≥ 8

7

1152

1.51(1.24,1.83)

1.19(0.67,2.13)

 

86.20%

0.000

  < 8

3

345

0.59(0.40,0.88)

0.67(0.17,2.57)

 

91.50%

0.000

Specimen

0.621

  

 blood

3

316

1.93(1.54,2.41)

1.93(1.54,2.41)

 

0.00%

0.878

 tissues

5

1181

0.69(0.53,0.90)

0.73(0.33,1.62)

 

88.30%

0.000

Tumor Category

0.350

  

 Gastrointestinal cancer

4

769

1.85(1.43,2.40)

1.85(1.43,2.40)

 

0.00%

0.402

 Non-gastrointestinal cancer

6

728

0.93(0.74,1.17)

0.65(0.26,1.61)

 

92.50%

0.000

  1. Abbreviations: 95%CI 95% confidence interval, Fixed Fixed effects model, HR hazard ratio, NOS Newcastle-Ottawa scale scores, Random Random pooling model