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Table 2 Changes in patient and BIA variables over time by PG-SGA at T0

From: Bioelectrical impedance analysis for monitoring cancer patients receiving chemotherapy and home parenteral nutrition

 

PG-SGA at T0

T0

T1

T2

Mean Slope

(change per day)

P

Patient Variables

 Actual body weight, kg

B

60.2 [57.5] (39.0–100.0)

62.3 [59.6] (41.5–96.0)

62.8 [60.0] (43.5–95.0)

0.03

0.01

C

54.9 [56.5] (33.0–85.5)

55.7 [56.4] (37.7–83.0)

56.8 [58.5] (37.5–80.0)

0.02

0.02

 Body Mass Index, kg/m2

B

22.0 [21.2] (14.5–39.1)

22.8 [21.9] (16.5–37.5)

23.0 [22.1] (17.2–37.1)

0.01

< 0.01

C

20.4 [20.7] (12.7–29.1)

20.8 [20.6] (15.4–28.1)

21.2 [20.7] (15.4–29.7)

0.01

0.02

 Oral calorie intake, kCal

B

744.7 [800] (0–1500)

1190.5 [1200] (0–2550)

1204.2 [1280] (0–2550)

5.44

< 0.01

C

462.4 [500] (0–1300)

642.1 [600] (0–1700)

735.3 [600] (0–1900)

3.03

< 0.01

 Oral protein intake, g/day

B

24.8 [25] (0–50)

40.6 [40] (0–110)

40.8 [45] (0–90)

0.19

< 0.01

C

17.6 [17.5] (0–50)

24.6 [25] (0–75)

28.8 [30] (0–60)

0.12

< 0.01

 Karnofsky PS

B

67.7 [70] (50–90)

NA

74.5 [80] (50–90)

NA

< 0.01

C

67.1 [70] (50–80)

NA

70.6 [70] (50–90)

NA

0.1

 ECOG PS

B

1.3 [1] (0–2)

NA

1.0 [1] (0–2)

NA

< 0.01

C

1.4 [1] (1–2)

NA

1.3 [1] (0–2)

NA

0.82

 Albumin, g/dL

B

3.4 [3.5] (1.9–4.5)

NA

3.7 [3.7] (2.8–4.4)

NA

0.02

C

3.4 [3.5] (1.9–4.4)

NA

3.4 [3.3] (2.2–4.6)

NA

0.70

 C-reactive protein, mg/L

B

17.7 [10.5] (0.4–71)

NA

17.3 [4.0] (0.1–140)

NA

0.41

C

15.7 [12.2] (0.9–73.2)

NA

10.1 [7.2] (0.1–56.5)

NA

0.11

 mGPS

B

1 [1] (0–2)

NA

0.6 [0] (0–2)

NA

0.07

C

1 [1] (0–2)

NA

0.6 [0] (0–2)

NA

0.10

BIA Variables

 Resistance, Ohm

B

560.0 [550.0] (401–720)

573.5 [586.0] (401–722)

567.3 [602.0] (407–698)

0.10

0.42

C

619.0 [625] (402–804)

598.4 [594] (405–898)

599.1 [610.0] (372–780)

−0.24

0.12

 Reactance, Ohm

B

45.4 [42.0] (19–118)

46.2 [42.6] (20–69)

44.8 [42.0] (23–72)

0.00

0.88

C

58.0 [53.0] (23–120)

55.5 [52.0] (25–99)

57.1 [51.5] (22–116)

− 0.01

0.69

 Phase Angle, °

B

4.5 [4.2] (2.5–7.5)

4.6 [4.5] (2.5–6.2)

4.5 [4.4] (2.3–6.3)

0.00

0.82

C

4.8 [4.8] (2.5–8.1)

5.0 [4.7] (2.5–11.4)

5.0 [4.5] (2.3–10.0)

0.00

0.30

 Total Body Water, %

B

59.5 [59.5] (39.3–76.6)

57.2 [58.1] (41.3–72.8)

56.9 [56.5] (42.0–72.0)

−0.03

< 0.01

C

59.4 [60.1] (40.3–85.8)

59.8 [60.0] (43.7–76.6)

58.9 [59.0] (41.7–76.4)

0.00

0.74

 Extracellular Water, %,

B

54.1 [56.1] (25.4–70.7)

53.8 [53.8] (44.9–69.9)

54.4 [54.4] (44.2–73.2)

0.00

0.89

C

50.4 [49.1] (31.7–68.5)

50.5 [50.5] (29.5–69.2)

50.2 [51.5] (32.3–71.3)

0.00

0.93

 Intracellular water, %

B

45.9 [43.9] (29.3–74.6)

46.6 [46.3] (30.1–55.1)

45.6 [45.6] (26.8–55.8)

0.00

0.95

C

49.6 [51.0] (31.5–68.3)

49.5 [49.6] (30.8–70.5)

49.5 [48.0] (28.7–67.7)

0.00

0.89

 Fat Mass, %

B

23.8 [25.4] (4.6–50.8)

26.2 [26.9] (0.5–48.4)

28.5 [29.1] (1.6–76.9)

0.05

0.02

C

22.8 [22.7] (−7.3–45.0)

22.1 [20.5] (1.2–45.4)

23.4 [21.6] (3.3–43.0)

0.00

0.78

 Fat Free Mass, %

B

74.4 [74.5] (49.2–86.9)

73.8 [73.1] (51.6–99.5)

73.2 [72.0] (52.2–98.4)

−0.01

0.401

C

75.0 [77.4] (55.0–85.4)

77.9 [79.6] (54.6–101.2)

76.6 [78.5] (57.0–96.7)

0.02

0.09

 Muscle Mass, %

B

42.6 [37.7] (25.7–144.6)

38.8 [36.9] (27.3–64.5)

38.2 [35.6] (24.2–79.9)

−0.05

0.20

C

45.2 [44.8] (25.3–98.1)

47.3 [44.6] (19.5–120.7)

45.6 [42.0] (23.5–81.3)

0.01

0.69

 ECM/BCM Index, %

B

1.6 [1.6] (−0.4–3.5)

1.6 [1.5] (0.4–3.5)

1.7 [1.5] (0.3–4.0)

0.00

0.82

C

1.3 [1.2] (0.3–3.8)

1.3 [1.3] (−0.1–3.7)

1.3 [1.2] (0.2–3.7)

0.00

0.69

  1. All values are expressed as median [median] (range), or percentage as indicated
  2. T0: at start of HPN; T1: 60 days after the start of HPN; T2: 90 days after the start of HPN
  3. BIA Bioelectrical impedance analysis, PG-SGA Patient-generated subjective global assessment; Category A = well-nourished; Category B = suspected malnutrition or moderate malnutrition; Category C = severely malnourished; NA Not applicable, PS Performance status, mGPS Modified Glasgow prognostic score