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Table 2 Changes in patient and BIA variables over time by PG-SGA at T0

From: Bioelectrical impedance analysis for monitoring cancer patients receiving chemotherapy and home parenteral nutrition

  PG-SGA at T0 T0 T1 T2 Mean Slope
(change per day)
P
Patient Variables
 Actual body weight, kg B 60.2 [57.5] (39.0–100.0) 62.3 [59.6] (41.5–96.0) 62.8 [60.0] (43.5–95.0) 0.03 0.01
C 54.9 [56.5] (33.0–85.5) 55.7 [56.4] (37.7–83.0) 56.8 [58.5] (37.5–80.0) 0.02 0.02
 Body Mass Index, kg/m2 B 22.0 [21.2] (14.5–39.1) 22.8 [21.9] (16.5–37.5) 23.0 [22.1] (17.2–37.1) 0.01 < 0.01
C 20.4 [20.7] (12.7–29.1) 20.8 [20.6] (15.4–28.1) 21.2 [20.7] (15.4–29.7) 0.01 0.02
 Oral calorie intake, kCal B 744.7 [800] (0–1500) 1190.5 [1200] (0–2550) 1204.2 [1280] (0–2550) 5.44 < 0.01
C 462.4 [500] (0–1300) 642.1 [600] (0–1700) 735.3 [600] (0–1900) 3.03 < 0.01
 Oral protein intake, g/day B 24.8 [25] (0–50) 40.6 [40] (0–110) 40.8 [45] (0–90) 0.19 < 0.01
C 17.6 [17.5] (0–50) 24.6 [25] (0–75) 28.8 [30] (0–60) 0.12 < 0.01
 Karnofsky PS B 67.7 [70] (50–90) NA 74.5 [80] (50–90) NA < 0.01
C 67.1 [70] (50–80) NA 70.6 [70] (50–90) NA 0.1
 ECOG PS B 1.3 [1] (0–2) NA 1.0 [1] (0–2) NA < 0.01
C 1.4 [1] (1–2) NA 1.3 [1] (0–2) NA 0.82
 Albumin, g/dL B 3.4 [3.5] (1.9–4.5) NA 3.7 [3.7] (2.8–4.4) NA 0.02
C 3.4 [3.5] (1.9–4.4) NA 3.4 [3.3] (2.2–4.6) NA 0.70
 C-reactive protein, mg/L B 17.7 [10.5] (0.4–71) NA 17.3 [4.0] (0.1–140) NA 0.41
C 15.7 [12.2] (0.9–73.2) NA 10.1 [7.2] (0.1–56.5) NA 0.11
 mGPS B 1 [1] (0–2) NA 0.6 [0] (0–2) NA 0.07
C 1 [1] (0–2) NA 0.6 [0] (0–2) NA 0.10
BIA Variables
 Resistance, Ohm B 560.0 [550.0] (401–720) 573.5 [586.0] (401–722) 567.3 [602.0] (407–698) 0.10 0.42
C 619.0 [625] (402–804) 598.4 [594] (405–898) 599.1 [610.0] (372–780) −0.24 0.12
 Reactance, Ohm B 45.4 [42.0] (19–118) 46.2 [42.6] (20–69) 44.8 [42.0] (23–72) 0.00 0.88
C 58.0 [53.0] (23–120) 55.5 [52.0] (25–99) 57.1 [51.5] (22–116) − 0.01 0.69
 Phase Angle, ° B 4.5 [4.2] (2.5–7.5) 4.6 [4.5] (2.5–6.2) 4.5 [4.4] (2.3–6.3) 0.00 0.82
C 4.8 [4.8] (2.5–8.1) 5.0 [4.7] (2.5–11.4) 5.0 [4.5] (2.3–10.0) 0.00 0.30
 Total Body Water, % B 59.5 [59.5] (39.3–76.6) 57.2 [58.1] (41.3–72.8) 56.9 [56.5] (42.0–72.0) −0.03 < 0.01
C 59.4 [60.1] (40.3–85.8) 59.8 [60.0] (43.7–76.6) 58.9 [59.0] (41.7–76.4) 0.00 0.74
 Extracellular Water, %, B 54.1 [56.1] (25.4–70.7) 53.8 [53.8] (44.9–69.9) 54.4 [54.4] (44.2–73.2) 0.00 0.89
C 50.4 [49.1] (31.7–68.5) 50.5 [50.5] (29.5–69.2) 50.2 [51.5] (32.3–71.3) 0.00 0.93
 Intracellular water, % B 45.9 [43.9] (29.3–74.6) 46.6 [46.3] (30.1–55.1) 45.6 [45.6] (26.8–55.8) 0.00 0.95
C 49.6 [51.0] (31.5–68.3) 49.5 [49.6] (30.8–70.5) 49.5 [48.0] (28.7–67.7) 0.00 0.89
 Fat Mass, % B 23.8 [25.4] (4.6–50.8) 26.2 [26.9] (0.5–48.4) 28.5 [29.1] (1.6–76.9) 0.05 0.02
C 22.8 [22.7] (−7.3–45.0) 22.1 [20.5] (1.2–45.4) 23.4 [21.6] (3.3–43.0) 0.00 0.78
 Fat Free Mass, % B 74.4 [74.5] (49.2–86.9) 73.8 [73.1] (51.6–99.5) 73.2 [72.0] (52.2–98.4) −0.01 0.401
C 75.0 [77.4] (55.0–85.4) 77.9 [79.6] (54.6–101.2) 76.6 [78.5] (57.0–96.7) 0.02 0.09
 Muscle Mass, % B 42.6 [37.7] (25.7–144.6) 38.8 [36.9] (27.3–64.5) 38.2 [35.6] (24.2–79.9) −0.05 0.20
C 45.2 [44.8] (25.3–98.1) 47.3 [44.6] (19.5–120.7) 45.6 [42.0] (23.5–81.3) 0.01 0.69
 ECM/BCM Index, % B 1.6 [1.6] (−0.4–3.5) 1.6 [1.5] (0.4–3.5) 1.7 [1.5] (0.3–4.0) 0.00 0.82
C 1.3 [1.2] (0.3–3.8) 1.3 [1.3] (−0.1–3.7) 1.3 [1.2] (0.2–3.7) 0.00 0.69
  1. All values are expressed as median [median] (range), or percentage as indicated
  2. T0: at start of HPN; T1: 60 days after the start of HPN; T2: 90 days after the start of HPN
  3. BIA Bioelectrical impedance analysis, PG-SGA Patient-generated subjective global assessment; Category A = well-nourished; Category B = suspected malnutrition or moderate malnutrition; Category C = severely malnourished; NA Not applicable, PS Performance status, mGPS Modified Glasgow prognostic score