Fig. 4
From: GPNMB methylation: a new marker of potentially carcinogenic colon lesions
Immunohistochemical staining of GPNMB in human tissue microarray. 1 mm core were used from each patient’s FFPE Block on the TMAs. a Positive GPNMB staining of brown color (DAB) represented in membrane in normal colon biopsies, some staining was also noted in the stroma. b Moderate cytoplasmic membrane staining marked in biopsy specimens from advanced adenoma. c CRC patients showed absence of GPNMB staining in the malignant cells. Statistical analysis was performed using the chi-square test