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Table 3 Multivariable Cox regression for cancer-specific mortality stratified by T and N stages

From: Long-term effects of neoadjuvant radiotherapy, adjuvant radiotherapy, and chemotherapy-only on survival of locally advanced non-small cell lung Cancer undergoing surgery: a propensity-matched analysis

Variable T1/2 & N2/3 T3/4 & N0/1 T3/4 & N2/3
(N = 746) (N = 294) (N = 238)
Age 1.01 (1.00, 1.02) 1.00 (0.98, 1.02) 1.03 (1.01, 1.05) **
Sex
 Male Ref. Ref. Ref.
 Female 0.81 (0.66, 1.01) 0.92 (0.63, 1.34) 0.97 (0.67, 1.40)
Race
 White Ref. Ref. Ref.
 Black 0.87 (0.62, 1.21) 0.80 (0.44, 1.45) 0.97 (0.57, 1.65)
 Others 0.97 (0.68, 1.38) 1.13 (0.54, 2.34) 0.88 (0.48, 1.62)
Grade
 I/ II Ref. Ref. Ref.
 III/ IV 1.34 (1.07, 1.67) * 1.67 (1.08, 2.58) * 0.93 (0.63, 1.37)
 Unknown 0.74 (0.51, 1.07) 0.66 (0.30, 1.44) 1.79 (0.93, 3.46)
Histology
 Adenocarcinoma Ref. Ref. Ref.
 Squamous cell 1.01 (0.77, 1.31) 0.69 (0.44, 1.07) 0.66 (0.42, 1.05)
 Others 0.98 (0.77, 1.25) 0.94 (0.61, 1.44) 0.72 (0.47, 1.11)
Extent of Surgery
 Lobectomy or Bilobectomy Ref. Ref. Ref.
 Pneumectomy 1.04 (0.76, 1.43) 1.00 (0.63, 1.59) 1.80 (1.25, 2.61) **
Treatment regimen
 Neoadjuvant RT Ref. Ref. Ref.
 Adjuvant RT 1.11 (0.84, 1.47) 1.54 (0.99, 2.38) 0.74 (0.47, 1.16)
 Chemotherapy-Only 1.42 (1.10, 1.83) ** 0.65 (0.42, 1.02) 0.93 (0.62, 1.41)
  1. * p < 0.05; ** p < 0.01