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Table 5 Correlation of cytoplasmic ERβ with expression of cancer-associated genes and steroid hormone receptors

From: Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer

 

CA125

CEA

CA72–4

EGFR

HER2

Ki-67

P53

ERα

ERβ (n)

PR

All

Spearman r

0.073

0.036

0.026

0.262

0.089

−0.012

0.037

−0.049

−0.085

0.131

95% CI

−0.086

− 0.227

−0.122

− 0.193

−0.132

- 0.183

0.106

- 0.405

−0.069

- 0.243

− 0.175

- 0.152

−0.121

- 0.194

− 0.205

- 0.109

−0.238

- 0.073

− 0.029

- 0.284

p value

n.s.

n.s.

n.s.

0.0009

n.s.

n.s.

n.s.

n.s.

n.s.

n.s.

Serous

Spearman r

−0.007

0.041

−0.026

0.238

0.020

0.174

0.083

−0.109

−0.078

0.202

95% CI

−0.183

- 0.17

−0.138

- 0.216

− 0.202

− 0.152

0.06

− 0.402

−0.158

- 0.197

− 0.010

- 0.346

−0.095

- 0.257

− 0.281

- 0.07

−0.252

- 0.099

0.023–0.3699

p value

n.s.

n.s.

n.s.

0.0075

n.s.

n.s.

n.s.

n.s.

n.s.

0.0231

  1. Correlations of cytoplasmic ERβ expression with expression of ovarian cancer markers CA125, CEA, CA72–4 and with EGFR, HER2, Ki-67, P53, ERα, nuclear ERβ (n) and PR were calculated for all ovarian cancers (“all”) and serous ovarian cancers (“serous”) using the Spearman correlation coefficient. P-values below 0.05 were considered statistically significant (significant results were indicated by using bold font)
  2. CI confidence interval