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Table 5 Correlation of cytoplasmic ERβ with expression of cancer-associated genes and steroid hormone receptors

From: Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer

  CA125 CEA CA72–4 EGFR HER2 Ki-67 P53 ERα ERβ (n) PR
All Spearman r 0.073 0.036 0.026 0.262 0.089 −0.012 0.037 −0.049 −0.085 0.131
95% CI −0.086
− 0.227
−0.122
− 0.193
−0.132
- 0.183
0.106
- 0.405
−0.069
- 0.243
− 0.175
- 0.152
−0.121
- 0.194
− 0.205
- 0.109
−0.238
- 0.073
− 0.029
- 0.284
p value n.s. n.s. n.s. 0.0009 n.s. n.s. n.s. n.s. n.s. n.s.
Serous Spearman r −0.007 0.041 −0.026 0.238 0.020 0.174 0.083 −0.109 −0.078 0.202
95% CI −0.183
- 0.17
−0.138
- 0.216
− 0.202
− 0.152
0.06
− 0.402
−0.158
- 0.197
− 0.010
- 0.346
−0.095
- 0.257
− 0.281
- 0.07
−0.252
- 0.099
0.023–0.3699
p value n.s. n.s. n.s. 0.0075 n.s. n.s. n.s. n.s. n.s. 0.0231
  1. Correlations of cytoplasmic ERβ expression with expression of ovarian cancer markers CA125, CEA, CA72–4 and with EGFR, HER2, Ki-67, P53, ERα, nuclear ERβ (n) and PR were calculated for all ovarian cancers (“all”) and serous ovarian cancers (“serous”) using the Spearman correlation coefficient. P-values below 0.05 were considered statistically significant (significant results were indicated by using bold font)
  2. CI confidence interval