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Table 4 Correlation of nuclear ERβ expression in ovarian cancer with expression of ovarian cancer markers, cancer-associated genes and steroid hormone receptors

From: Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer

  CA125 CEA CA72–4 EGFR HER2 Ki-67 P53 ERα PR
All Spearman r −0.041 0.31 0.216 0.054 0.045 −0.084 0.101 0.086 0.006
95% CI −0.198
- 0.117
0.16
- 0.447
0.06
- 0.362
−0.107
- 0.213
− 0.114
- 0.201
− 0.246
- 0.083
− 0.058
- 0.255
− 0.073
- 0.240
− 0.154
- 0.166
P value n.s. < 0.0001 0.0057 n.s. n.s. n.s. n.s. n.s. n.s.
Serous Spearman r 0.051 0.345 0.264 0.089 0.098 −0.061 0.067 0.095 0.011
95% CI −0.129 - 0.227 0.177
- 0.493
0.089
- 0.423
−0.0940 - 0.266 −0.083 - 0.274 − 0.245 - 0.128 −0.113 - 0.242 − 0.084 - 0.269 −0.170 - 0.193
P value n.s. < 0.0001 0.0026 n.s. n.s. n.s. n.s. n.s. n.s.
  1. Correlation of nuclear ERβ expression with expression of ovarian cancer markers CA125, CEA, CA72–4, and with EGFR, HER2, Ki-67, P53, ERα and PR were calculated for all ovarian cancers (“all”) and serous ovarian cancers (“serous”) using the Spearman correlation coefficient. P-values below 0.05 were considered statistically significant (significant results were indicated by using bold font)
  2. CI confidence interval