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Table 4 Correlation of nuclear ERβ expression in ovarian cancer with expression of ovarian cancer markers, cancer-associated genes and steroid hormone receptors

From: Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer

 

CA125

CEA

CA72–4

EGFR

HER2

Ki-67

P53

ERα

PR

All

Spearman r

−0.041

0.31

0.216

0.054

0.045

−0.084

0.101

0.086

0.006

95% CI

−0.198

- 0.117

0.16

- 0.447

0.06

- 0.362

−0.107

- 0.213

− 0.114

- 0.201

− 0.246

- 0.083

− 0.058

- 0.255

− 0.073

- 0.240

− 0.154

- 0.166

P value

n.s.

< 0.0001

0.0057

n.s.

n.s.

n.s.

n.s.

n.s.

n.s.

Serous

Spearman r

0.051

0.345

0.264

0.089

0.098

−0.061

0.067

0.095

0.011

95% CI

−0.129 - 0.227

0.177

- 0.493

0.089

- 0.423

−0.0940 - 0.266

−0.083 - 0.274

− 0.245 - 0.128

−0.113 - 0.242

− 0.084 - 0.269

−0.170 - 0.193

P value

n.s.

< 0.0001

0.0026

n.s.

n.s.

n.s.

n.s.

n.s.

n.s.

  1. Correlation of nuclear ERβ expression with expression of ovarian cancer markers CA125, CEA, CA72–4, and with EGFR, HER2, Ki-67, P53, ERα and PR were calculated for all ovarian cancers (“all”) and serous ovarian cancers (“serous”) using the Spearman correlation coefficient. P-values below 0.05 were considered statistically significant (significant results were indicated by using bold font)
  2. CI confidence interval