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Table 4 Univariate and multivariate regression analysis to identify predictors for hepatotoxicity related to erlotinib administration in pancreatic cancer patients

From: Risk factors for erlotinib-induced hepatotoxicity: a retrospective follow-up study

Characteristics

Unadjusted OR

(95% CI)

Adjusted OR

(95% CI)

Male

0.957 (0.491–1.865)

1.279 (0.598–2.737)

Age ≥ 65

0.858 (0.444–1.656)

0.731 (0.369–1.448)

BSA ≥ 1.6a

0.652 (0.336–1.268)

0.549 (0.255–1.180)

CYP3A4 Inducer

3.690 (0.886–15.679)

4.114 (0.969–17.465)

  1. For multivariate analysis, factors with p < 0.1 in the univariate analysis were included in addition to sex, age and BSA
  2. BSA body surface area
  3. aThere was 1 missing data for BSA