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Table 2 Univariate and multivariate regression analysis to identify predictors for hepatotoxicity related to erlotinib administration

From: Risk factors for erlotinib-induced hepatotoxicity: a retrospective follow-up study

Characteristics Unadjusted OR
(95% CI)
Adjusted OR
(95% CI)
Attributable
risk
Male 0.826 (0.475–1.437) 0.987 (0.516–1.886)  
Age ≥ 65 1.316 (0.760–2.280) 1.257 (0.718–2.203)  
BSA ≥ 1.6a 0.730 (0.422–1.263) 0.728 (0.383–1.385)  
Liver metastasis 1.717 (0.934–3.156) 1.862 (1.001–3.465)* 46.3
CYP3A4 Inducer 2.401 (0.936–6.162) 2.660 (1.013–6.982)* 62.4
  1. For multivariate analysis, factors with p < 0.1 in the univariate analysis were included in addition to sex, age and BSA
  2. BSA body surface area
  3. aThere was 1 missing data for BSA
  4. *P < 0.05