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Table 3 Relationship between FAM19A4 methylation and clinicopathological parameters in cervical cancer

From: The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre)cancer in Chinese women

Parameters

Median Methylation

Methylation Rates

U

P*

Scores(\( \mathrm{P}\frac{1}{4}-\mathrm{P}\frac{3}{4} \))

(%)

Age

< 48

144.14(49.89–387.46)

90.63(29/32)

445.00

0.784

≥48

140.65(62.20–466.41)

96.55(28/29)

Histology

SCC

145.37(62.54–450.44)

94.44(51/54)

144.00

0.321

AC/ASC

137.83(8.38–207.24)

85.71(6/7)

Stage

IA or IB1

153.17(67.84–387.46)

91.67(33/36)

409.00

0.548

IB2 or above

97.78(51.19–562.08)

96.00(24/25)

Size

≤4 cm

141.42(62.20–389.23)

93.88(46/49)

279.00

0.786

> 4 cm

123.54(23.42–807.25)

91.67(11/12)

Lymph node metastasis

yes

167.28(77.43–604.86)

100(10/10)

227.00

0.585

no

140.65(55.49–366.61)

92.16(47/51)

  1. SCC squamous cell carcinoma, AC adenocarcinoma, ASC adenosquamous carcinoma
  2. *P>0.05,Mann-Whitney U Test, methylation scores were used to calculate the statistical difference