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Fig. 1 | BMC Cancer

Fig. 1

From: Chronic active Epstein-Barr virus infection of T-cell type, systemic form in an African migrant: case report and review of the literature on diagnostics standards and therapeutic options

Fig. 1

Detection of Chronic Active Epstein-Barr-Virus infection associated T-cell-lymphoproliferative disease. a PET-CT showed suspect glucose uptake in the thyroid (➔), liver (), as well as in the iliac crest (*). b Targeted bone marrow biopsy revealed aggregates of intravascular pleomorphic cells (HE, × 200). Immunohistochemistry confirmed positivity for CD3 (c) and Perforin (d). Furthermore EBER-CISH demonstrated active EBV infection within these T-cells (e). f Subsequently T-cell receptor clonality analysis resulted a polyclonal T-cell population (vγ1–8, vγ10)

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