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Table 4 Univariate and multivariate analyses of variables for disease-free survival in STS patients

From: Prognostic value of the fibrinogen/albumin ratio (FAR) in patients with operable soft tissue sarcoma

Variables DFS Univariate analysis DFS Multivariate analysis
HR (95% CI) p-value HR (95% CI) p-value
Sex
 Male 1 (referent)    
 Female 1.014 (0.730–1.409) 0.934   
Age (years)
 < 50 1 (referent)   1 (referent)  
 ≥ 50 1.538 (1.103–2.145) 0.011 1.601 (1.111–2.306) 0.012
Tumor size (cm)
 < 5 1 (referent)    
 ≥ 5 2.181 (1.537–3.093) <0.001   
Tumor depth
 Superficial 1 (referent)   1 (referent)  
 Deep 3.006 (2.043–4.422) <0.001 2.346 (1.541–3.571) <0.001
Tumor grade
 G1 1 (referent)   1 (referent)  
 G2 2.268 (1.340–3.837) 0.002 1.798 (1.053–3.069) 0.031
 G3 5.300 (3.132–8.71) <0.001 4.404 (2.565–7.561) <0.001
AJCC stage
 IA + IB 1 (referent)    
 IIA + IIB 2.294 (1.402–3.751) 0.001   
 III + IV 5.089 (3.014–8.590) <0.001   
NLR
 < 2.51 1 (referent)   1 (referent)  
 ≥ 2.51 1.778 (1.271–2.487) 0.001 1.719 (1.195–2.471) 0.003
PLR
 < 191.1 1 (referent)    
 ≥ 191.1 2.498 (1.688–3.698) <0.001   
FAR
 < 0.0726 1 (referent)    
 ≥ 0.0726 1.956 (1.408–2.718) <0.001