From: Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL
Pt no.
Treatment regimen
Fold change in mRNA post-treatment
MCL-1
BAX
TCHL_39
TCH
1.1
0.9
TCHL_45
1.6
0.7
TCHL_50
1.0
0.8
TCHL_6
1.4
1.2
TCHL_29
TCL
TCHL_44
TCHL
TCHL_54
TCHL_7
1.3